Prevalens av hjertesvikt og klaffesykdom i Botswana; en befolkningsundersøkelse

Vitenskapelig tittel:
Prevalence of Heart Failure and Valvular Heart Disease in Botswana: A Population-based Study Evidence from developed countries suggests that HIV infection increases the risk of cardiovascular disease (CVD) by up to 50%. With improved survival on antiretroviral drugs (ARVs), heart failure (HF) has become a major complication among patients with HIV/AIDS. Valvular heart disease (VHD), including rheumatic heart disease (RHD) is one of the important CVDs in adults in sub-Saharan Africa (SSA). The advent of portable echocardiography allows screening for both HF and VHD, and can contribute to new population-based incidence estimates. Epidemiological data on these conditions is lacking in Botswana. We will screen at least 800 patients in a community setting using portable echocardiography, to determine the prevalence of HF and VHD. We will then assess how HIV-status affects such conditions. The proposed work will take place in clinics in the capital Gaborone for a period of 4 months in 2018.

Clinical epidemiological data regarding HIV/AIDS-related cardiovascular diseases in Botswana is currently lacking. Cardiovascular diseases are on the rise in middle income countries like Botswana, and are posing a major public health problem. Data on prevalence of heart failure and valvular heart disease and how HIV-status affects the timing and presentation of such conditions is lacking. In a collaborative study between the University of Botswana and MInistry of Health, we will perform a cross-sectional study that randomly include a minimum of 800 patients from the community. Participants will be screened with portable echocardiography and assessed for prevalence of heart failure and valvular heart disease, and then stratified according to HIV-status.
(Prosjektleders prosjektbeskrivelse)

Ref. nr.: 2017/2230 Prosjektstart: 03.09.2018 Prosjektslutt: 31.12.2020

Behandlingsstatus: Godkjent
Prosjektleder: Thusego Motswakadikgwa
Forskningsansvarlig(e):  University of Bergen
Initiativtaker: Bidragsforskning

University of Bergen, Norway on behalf of the Norwegian Embassy

Forskningsdata: Registerdata, Mennesker

Behandlet i REK
30.11.2017 REK sør-øst